All Articles Tagged As: disease

Extent of inbreeding in pedigree dogs revealed in new study (8/17/2008)

Study explores inbreeding, which puts dogs at risk of birth defects and genetically inherited health problems ...> Full Article

Large reservoir of mitochondrial DNA mutations identified in humans (8/12/2008)

Researchers have revealed a large reservoir of mitochondrial DNA mutations present in the general population. The findings highlight the need to develop new approaches to prevent the transmission of mitochondrial diseases. ...> Full Article

Complexity of Crohn's disease revealed as 'gene' count tops 30 (7/6/2008)

New research has trebled the number of genetic regions known to be implicated in Crohn's disease, a form of inflammatory bowel disease, to over thirty ...> Full Article

Our genome changes over lifetime (6/25/2008)

May explain many 'late-onset' diseases ...> Full Article

Drug reverses mental retardation caused by genetic disorder (6/23/2008)

Mouse study offers hope for correcting how autism disrupts brain ...> Full Article

Novel DNA microarray chip predicts functional impairment and remission in rheumatoid arthritis (6/21/2008)

A new DNA microarray chip can predict severe disability and remission in patients with rheumatoid arthritis ...> Full Article

EuroDYNA takes lid off the genome (6/16/2008)

European researchers have made significant progress unravelling how genes are governed and why this sometimes goes wrong in disease. The key lies in the dynamic ever-changing structure of the chromatin ...> Full Article

Scientists reveal the genetics of fat storage in cells (5/29/2008)

Scientists devised a genetic screen to identify genes responsible for fat storage in cell of fruit flies, and potentially other species. ...> Full Article

Research Suggests Abnormal 'Editing' of Gene Messages a Cause of Lupus (5/26/2008)

Researchers have uncovered evidence that the abnormal "editing" of gene messages in a type of white blood cell may be behind the development of lupus ...> Full Article

First genome-wide scan for osteoporosis (5/1/2008)

Research has uncovered two genes to aid diagnosis and treatment of osteoporosis. ...> Full Article

Analysis Of RNA Role In Spreading Disease Advances Study Of Damaging Plant Infections (4/24/2008)

Recent research that links specific pieces of RNA to an infectious organism's duplication and spread could lead the way to the prevention of viroids, pathogens that can kill or damage food crops and other plants. ...> Full Article

Researchers Discover Critical Detail of Cellular Defense Against Genetic Mistakes (4/19/2008)

Researchers are closing in on a completed diagram of how human cells protect themselves against constant genetic mistakes that contribute to most diseases ...> Full Article

A genetic cause for iron deficiency (4/14/2008)

Rare syndrome may provide general insight into iron deficiency, and suggests new treatments for iron disorders ...> Full Article

Technique traces origins of disease genes in mixed races (4/12/2008)

A team of researchers has developed a technique to detect the ancestry of disease genes in hybrid, or mixed, human populations. ...> Full Article

Autism Gene Scans Converge on Two Suspect Sites, Two Types of Genetic Risk (3/22/2008)

Four teams of scientists, using resources supported in part by NIMH, have pinpointed two different sites in the genome, each conferring a different type of genetic risk for autism. At one site, risk genes appear to be inherited. At the other, risk stems from spontaneous mutations, not seen in the genetics of the parents. In both examples, evidence suggests the suspect genes are critical for development of brain circuits impaired in autism. ...> Full Article

Structural Genomic Variation and Personalized Medicine (2/24/2008)

The ultimate goal of personalized medicine is to comprehensively identify genetic differences among persons and to correlate specific genetic features (or combinations of genetic features) with the differential risk of human diseases or the efficacy of certain therapeutic interventions. "This goal is likely to be achieved when we are able to identify all relevant forms of genetic variation in each person and are able to interpret this information in a clinically meaningful manner," said researchers from Harvard Medical School in their article recently published in The New England Journal of Medicine. ...> Full Article

Gene guards grain-producing grasses so people and animals can eat (2/4/2008)

Purdue University and USDA-Agricultural Research Service scientists have discovered that a type of gene in grain-producing plants halts infection by a disease-causing fungus that can destroy crops vital for human food supplies. ...> Full Article

Researchers discover new muscular dystrophy gene (1/31/2008)

Discovery may lead to better diagnosis and treatment ...> Full Article

Search For The 'On' Switches May Reveal Genetic Role In Development And Disease (1/26/2008)

A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP). ...> Full Article

Scientists Discover New Gene Linked to Fragile X Syndrome (1/24/2008)

Discovery Suggests Potential Targets for Autism and Other Neurological Disorders ...> Full Article

Major European Project to Create New Knowledge Base of Gene-Disease Relationships (1/23/2008)

12M Euro project will provide improved access to information connecting genes with diseases such as diabetes, obesity, heart disease and cancer ...> Full Article

Researcher In RNA Biology Makes Waves By Challenging Current Thinking (1/21/2008)

In the January 18th issue of Molecular Cell, Case Western Reserve University School of Medicine researcher Kristian E. Baker, Ph.D. challenges molecular biology's established body of evidence and widely-accepted model for nonsense-mediated messenger ribonucleic acid (mRNA) decay. With her collaborator, Ambro van Hoof, Ph.D. of The University of Texas Health Sciences Center, Baker directly tested the "faux 3' UTR" model and proved it could not explain how cells recognize and destroy deviant mRNA. This landmark discovery will redirect mRNA research and expand opportunities for new discoveries in understanding the cells' ability to protect itself from these potential errors. ...> Full Article

Tiny Genetic Differences Have Huge Consequences (1/20/2008)

A study led by McGill University researchers has demonstrated that small differences between individuals at the DNA level can lead to dramatic differences in the way genes produce proteins. These, in turn, are responsible for the vast array of differences in physical characteristics between individuals. ...> Full Article

A new piece in the autism puzzle (1/13/2008)

Genome scan finds missing DNA may play role in cognitive disorder ...> Full Article

Recurrent genetic deletion linked to autism (1/9/2008)

Loss of a small portion of chromosome 16, known as 16p11.2, is significantly associated with autism report researchers from the University of Chicago Medical Center, the University of Illinois at Chicago, and the Roswell Park Cancer Institute in an article, published Dec. 21, 2007, online by the journal Human Molecular Genetics. ...> Full Article

Breakthrough could save the Tasmanian Devil (10/3/2007)

Sydney University researchers have discovered why the Devil Facial Tumour Disease which has wiped out 90 per cent of some native Tasmanian Devil populations has been so devastating. ...> Full Article

'Genes and Environment' grant funds close look at nature-nurture overlap in common diseases (9/25/2007)

Johns Hopkins' McKusick-Nathans Institute of Genetic Medicine is one of two gene-hunting facilities in the nation to win a new $11.7 million four-year federal grant to rigorously sort out how such environmental factors as diet, exercise, stress and addictions interact with people's individual genetic makeup to affect their risk for disorders as wide-ranging as cancer, diabetes, tooth decay and heart disease. ...> Full Article