All Articles Tagged As: epigenetics

Our genome changes over lifetime (6/25/2008)

May explain many 'late-onset' diseases ...> Full Article

RNA induction of an epigenetic hereditary pathology (6/10/2008)

A new study shows that microinjection of RNA molecules into mouse embryos induces a hereditary form of cardiac hypertrophy that is similar to human hypertrophic cardiomyopathy ...> Full Article

Protocols features classic approaches for analyzing chromosomes (5/2/2008)

Two classic methods for chromosomal analysis ...> Full Article

Epigenetic research uncovers new targets for modification enzymes (4/28/2008)

Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows ...> Full Article

Scientists Clarify a Mechanism of Epigenetic Inheritance (4/23/2008)

"Silent" DNA stays that way as a result of RNA interference during chromosome replication ...> Full Article

Charting the Epigenome (4/18/2008)

Until recently, the chemical marks littering the DNA inside our cells like trees dotting a landscape could only be studied one gene at a time. But new high-throughput DNA sequencing technology has enabled researchers to map the precise position of these individual DNA modifications throughout the genome of the plant Arabidopsis thaliana, and chart its effect on the activity of any of Arabidopsis' roughly 26,000 genes. ...> Full Article

Brain DNA 'Remodeled' in Alcoholism (4/3/2008)

Reshaping of the DNA scaffolding that supports and controls the expression of genes in the brain may play a major role in the alcohol withdrawal symptoms, particularly anxiety, that make it so difficult for alcoholics to stop using alcohol. ...> Full Article

Epigenetic changes discovered in major psychosis (3/12/2008)

New clues for uncovering the mysteries of mental illness ...> Full Article

New revelations in epigenetic control shed light on breast cancer (3/11/2008)

Scientists discover that long-term regulation of the human genome is much more dynamic than assumed ...> Full Article

Protocols features high-throughput methods for analyzing gene activity (3/9/2008)

New high-throughput methods are revolutionizing our understanding of transcriptional regulation ...> Full Article

Mice with gene deletion provide clues to Prader-Willi syndrome in study (3/5/2008)

A new mouse model for a genetic cause of obesity has been developed by scientists at the Stanford University School of Medicine and Lucile Packard Children's Hospital. The researchers hope that learning more about the mice, which overeat but do not gain weight, will help them develop new therapies for people with Prader-Willi syndrome, a rare genetic condition that triggers uncontrollable eating. ...> Full Article

Genome-wide profiling of epigenetic therapy in cervical cancer (2/26/2008)

In a single-arm interventional study, demethylating hydralazine and the histone deacetylase (HADC) inhibitor magnesium valproate were added to cisplatin chemoradiation in International Federation of Gynecology and Obstetrics (FIGO) stage IIIB cervical cancer treatment to assess their safety and biological effects. ...> Full Article

Environmental Epigenetics Has Potential for Preventing and Treating Disease (2/2/2008)

New research on environmental influences on health and disease has begun to shed light on why genetically identical individuals demonstrate different characteristics, such as susceptibility to disease. Scientists have found that environmental exposure to nutritional, chemical and physical factors can alter the epigenome. Literally meaning "above the genome," the epigenome refers to differences in gene expression that are inherited without changing the sequence of DNA. ...> Full Article