All Articles Tagged As: epigenomics
 | Although the human genome sequence faithfully lists (almost) every single DNA base of the roughly 3 billion bases that make up a human genome, it doesn't tell biologists much about how its function is regulated. Now, researchers at the Salk Institute provide the first detailed map of the human epigenome, the layer of genetic control beyond the regulation inherent in the sequence of the genes themselves. ...> Full Article |
The National Institutes of Health announced today that it will fund 22 grants on genome-wide studies of how epigenetic changes -- chemical modifications to genes that result from diet, aging, stress, or environmental exposures -- define and contribute to specific human diseases and biological processes.
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 | The study of eipigenetic variability in cells and tissues could someday help diagnose diseases more precisely and provide more targeted treatments for chronic ailments. Details, summarized by Brown University researchers and others, are published online in the latest edition of PLoS Genetics. ...> Full Article |
Researchers have uncovered a vast new class of previously unrecognized mammalian genes that do not encode proteins, but instead function as long RNA molecules, and seem to play critical roles in both health and disease, including cancer, immune signaling and stem cell biology.
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New research on environmental influences on health and disease has begun to shed light on why genetically identical individuals demonstrate different characteristics, such as susceptibility to disease. Scientists have found that environmental exposure to nutritional, chemical and physical factors can alter the epigenome. Literally meaning "above the genome," the epigenome refers to differences in gene expression that are inherited without changing the sequence of DNA.
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