All Articles Tagged As: gene regulation

Protocols features classic approaches for analyzing chromosomes (5/2/2008)

Two classic methods for chromosomal analysis ...> Full Article

Pathway Found That Lets Mosquitoes Fatten Up, Slow Down For Winter (4/25/2008)

Two genes that help insulin regulate mosquitoes' growth have been identified as key contributors to how the insects enter a dormant state to survive winter's cold. ...> Full Article

Plant researchers publish finding on enzyme, drought connection (4/20/2008)

A better understanding of how plants tolerate drought could result ...> Full Article

Computation to unravel how genes are regulated and shed light on how cells become different (4/11/2008)

A closer alliance between computational and experimental researchers is needed to make progress towards one of biology's most challenging goals, understanding how epigenetic marks contribute to regulation of gene expression ...> Full Article

Researchers rise to the occasion for yeast study (4/9/2008)

Scientists have found a vital missing link for the regulation of genes essential for cell metabolism. ...> Full Article

Less can be more, for plant breeders too (3/25/2008)

Imagine you are a rice breeder and one day within a large field you discover a plant that has just the characteristics you have been looking for. You happily take your special plant to the laboratory where you find out that the spontaneous, beneficial event was due to inactivation of a single gene. This is a great observation; however, there are many different strains grown in different parts of the world, well adapted to the particular region they grow in. How can you now transfer the inactivated gene to other strains of rice? Conventionally, you would have to go through years and years of breeding, until you have successfully transferred that single gene, without affecting all the other genes that are responsible for the target strains being so well adapted to their local environment. Would it not be great, if one could do this faster? ...> Full Article

Protocols features high-throughput methods for analyzing gene activity (3/9/2008)

New high-throughput methods are revolutionizing our understanding of transcriptional regulation ...> Full Article

Device allows scientists to control gene activity across generations of cells (3/4/2008)

Just as cells inherit genes, they also inherit a set of instructions that tell genes when to become active, in which tissues and to what extent. Now, Rockefeller University researchers have built a device that, by allowing scientists to turn genes on and off in actively multiplying budding yeast cells, will help them figure out more precisely than before how genes and proteins interact with one another and how these interactions drive cellular functions. ...> Full Article

Toolkit energizes study of cell's powerhouse (2/27/2008)

Screening both genes and physiology yields rich compendium on mitochondrial biology ...> Full Article

Gene at intersection of stem cells, immunity (2/25/2008)

A gene that "wakes up" the blood system's stem cells in times of stress also plays an important role in protecting against infection, said researchers from Baylor College of Medicine in Houston, the National Institute of Allergy and Infectious Disease and Duke University Medical School in a report that appears in the journal Cell Stem Cell. ...> Full Article

Scientists Discover New Details of a Gene-Regulatory Network Governing Metabolism (2/23/2008)

A molecule called NADP regulates a cascade enabling yeast cells to adjust metabolic state ...> Full Article

Australian technology licensed by billion-dollar US company (2/14/2008)

Scientists have developed a proprietary technology that will help other researchers in understanding fundamental aspects of growth, development, and disease, which has been licensed to one of the world's largest life science technology companies. ...> Full Article

Scientists find how a protein binds to genes and regulates them across the human genome (2/11/2008)

Out of chaos, control: Cornell molecular biologists have discovered how a protein called PARP-1 binds to genes and regulates their expression across the human genome. Knowing where PARP-1 is located and how it works may allow scientists to target this protein to battle common diseases, such as stroke and cancer. ...> Full Article

Disrupted genetic regulation causes common disturbance in metabolism of fat (2/6/2008)

The disease familial combined hyperlipidemia (FCH) is a common cause of disturbed metabolism of fat and early heart attacks. Uppsala University scientists have now developed a pioneering method and can show for the first time what genes are regulated by the gene USF1, which is known to cause the disease. These findings are being presented today in the leading journal Genome Research. ...> Full Article

Environmental Epigenetics Has Potential for Preventing and Treating Disease (2/2/2008)

New research on environmental influences on health and disease has begun to shed light on why genetically identical individuals demonstrate different characteristics, such as susceptibility to disease. Scientists have found that environmental exposure to nutritional, chemical and physical factors can alter the epigenome. Literally meaning "above the genome," the epigenome refers to differences in gene expression that are inherited without changing the sequence of DNA. ...> Full Article

Molecular Evolution: Mice Given Bat-like Forelimbs Through Gene Switch (1/16/2008)

A research team led by Dr. Richard Behringer at MD Anderson Cancer Center reports that they have successfully switched the mouse Prx1 gene regulatory element with the Prx1 gene regulatory region from a bat -- and although these two species are separated by millions of years of evolution -- the resulting transgenic mice displayed abnormally long forelimbs. ...> Full Article

Researchers report new twist in microRNA biology (1/11/2008)

Computational biology group identifies new mechanism of gene regulation ...> Full Article

Mechanics of gene transcription (1/9/2008)

The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" within a cell nucleus, according to Cornell researchers. Instead, the enzyme RNA polymerase II (Pol II) and other key molecules can assemble at the site of an activated gene, regardless of the gene's position. ...> Full Article