All Articles Tagged As: gene silencing

RNA interference found in budding yeasts (9/15/2009)

Some budding yeast species have the ability to silence genes using RNA interference (RNAi). Until now, most researchers thought that no budding yeasts possess the RNAi pathway because Saccharomyces cerevisiae, the protoypical model budding yeast does not. Some budding yeasts cause human diseases, while other budding yeasts are used in research as models for more complicated organisms, in industry to create beer and biofuels, and in pharmaceuticals to produce drugs and vaccines. ...> Full Article

Female human embryos adjust the balance of X chromosomes before implantation (7/1/2009)

Results have implications for in vitro fertilisation and embryonic stem cell research ...> Full Article

Nanotechnology holds promise for STD drug delivery (5/5/2009)

Yale researchers describe a breakthrough in safe and effective administration of potential antiviral drugs -- small interfering RNA (siRNA) molecules that silence genes -- the first step in development of a new kind of treatment for sexually transmitted diseases (STDs). The work is reported May 4 as an advance online publication of Nature Materials. ...> Full Article

New nucleotide could revolutionize epigenetics (4/19/2009)

The discovery of a new nucleotide in the mouse brain opens the door to a new domain of epigenetic DNA modification ...> Full Article

A new gene silencing platform - silence is golden (2/18/2009)

Findings may lead to novel treatments for diseases resistant to current RNAi ...> Full Article

A new gene silencing platform -- silence is golden (2/10/2009)

Findings may lead to novel treatments for diseases resistant to current RNAi ...> Full Article

Silencing of jumping genes in pollen (2/7/2009)

Scientists at the Instituto Gulbenkian de Ciência, in Portugal, are to date the only research group in the world capable of isolating the sperm cells in the pollen grain of the model plant Arabidopsis thaliana. This technique was crucial in a study to be published in the latest issue of the journal Cell, which describes how mobile sequences of DNA (called transposable elements) are silenced in the sperm cells, thus ensuring suppression of the mutagenic effects of these DNA elements. ...> Full Article

Researchers solve piece of large-scale gene silencing mystery (12/9/2008)

Opening the 'X-files' of biology ...> Full Article

Model unravels rules that govern how genes are switched on and off (12/9/2008)

Now, scientists at Washington University School of Medicine in St. Louis report they have developed a model of gene expression in yeast that predicts with a high degree of accuracy whether a gene will be switched on or off. enes operate in each cell type at different times, and this careful orchestration is what ultimately distinguishes a brain cell from a liver or skin cell. ...> Full Article

New gene-silencing pathway found in plants (11/19/2008)

Shedding light on the 'dark matter' of genetics ...> Full Article

Seeing the Shape of Gene Silencing (9/22/2008)

Researchers have devised clever new techniques to mimic the chemical marks on tightly wound DNA-protein complexes that silence gene expression. The scientists have used these complexes to visualize gene silencing in its natural context for the first time. ...> Full Article

Researchers discover technology that silences genes (8/20/2008)

Suppressing disease-causing genes is now within reach ...> Full Article

Class of antibiotics can enhance gene-silencing tool (7/22/2008)

Researchers have discovered that antibiotics known as fluoroquinolones can make RNA interference more effective in the laboratory and reduce potential side effects ...> Full Article

Genome communication (6/28/2008)

Alleles of homologous genes can silence one another through paramutations ...> Full Article

Novel 'Gene Toggles' In Rice, World's Top Food Crop (4/15/2008)

Researchers have found a new type of molecule--a kind of "micro-switch"--that can turn off genes in rice, which is the primary source of food for more than half the world's population. ...> Full Article

Physician Revolutionizes Gene Research (4/1/2008)

A dramatic new study questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes. ...> Full Article

Gene 'Knockout' Floors Tobacco Carcinogen (3/20/2008)

Scientists have shown that silencing a specific gene in burley tobacco plants significantly reduces harmful carcinogens in cured tobacco leaves. ...> Full Article

Researchers discover protein sequence that governs whether a plant grows a root or shoot (2/9/2008)

Controlled by a tightly regulated choreography that determines what should go up and what should go down, plants develop along a polar axis with a root on one end and a shoot on the other. ...> Full Article

Scientists Discover New Gene Linked to Fragile X Syndrome (1/24/2008)

Discovery Suggests Potential Targets for Autism and Other Neurological Disorders ...> Full Article