All Articles Tagged As: genomics

Microbes beneath sea floor genetically distinct (7/23/2008)

Tiny microbes beneath the sea floor, distinct from life on the Earth's surface, may account for one-tenth of the Earth's living biomass ...> Full Article

Review article provides tools for the Rosaceae genomics community (7/13/2008)

Comprehensive overview of the genomics tools and resources available for the rapidly growing Rosaceae scientific community ...> Full Article

Enzyme key to 'sister act' that maintains genome stability (7/11/2008)

Keeping the genome stable is a "sister act" of matched chromatids - the pairs of the double helix DNA molecule that exist during the chromosome duplication in the S phase of the cell cycle. ...> Full Article

Deep sequencing study reveals new insights into human transcriptome (7/10/2008)

Project takes the first step towards a new picture of the mammalian genome annotation ...> Full Article

Duckweed genome sequencing has global implications (7/9/2008)

Pond scum can undo pollution, fight global warming and alleviate world hunger ...> Full Article

Creating a new approach to archiving human genetic information (7/8/2008)

Scientists create wiki style system for gene annotation. ...> Full Article

Genomics Research Focuses on Rice Variety Improvement (7/7/2008)

Crop varieties can be improved through the study of genomics without creating genetically transformed varieties. ...> Full Article

US Department of Energy Joint Genome Institute announces new genome sequencing projects (7/5/2008)

Pine tree, boat-boring bivalve 'bugs,' duck weed, oil-producing microalgae, stinkbird gut, 40 others top 2009 targets ...> Full Article

How to build a plant (6/30/2008)

Plant architecture from the genomics toolbox ...> Full Article

Meet the genome's puzzle masters (6/29/2008)

Making sense of genomic data can be a real puzzler, but computational researchers know how to put the pieces together ...> Full Article

Unlocking genome of world's worst insect pest (6/19/2008)

Scientists are on the brink of a discovery which will facilitate the development of new, safe, more sustainable ways of controlling the world's worst agricultural insect pest - the moth, Helicoverpa armigera. ...> Full Article

Genetics research could lead to tailor-made pigs (6/15/2008)

Geneticist has provided a boost to pig producers wanting to tailor their animals to specific markets ...> Full Article

Joint venture bolsters genomic sequencing capabilities (6/10/2008)

Joint venture acquires two new instruments that provide an enhanced ability to sequence genomes more quickly and broadly. ...> Full Article

Face-to-face search for genetic switches (6/9/2008)

A new investigation into how genes determine our facial appearance is to be launched ...> Full Article

Brucella abortus S19 genome sequenced; points toward virulence genes (6/8/2008)

Geneticists have sequenced the genome of Brucella abortus strain S19. Strain S19 is a naturally occurring strain of B. abortus that does not cause disease ...> Full Article

The good news in our DNA: Defects you can fix with vitamins and minerals (6/7/2008)

Personal genomes may lead to personalized vitamin supplements ...> Full Article

A common aquatic animal's genome can capture foreign DNA (6/2/2008)

Apparent ease of DNA incorporation may reveal a bizarre new form of sexual reproduction ...> Full Article

Statistical tool could explain gene study variations (5/30/2008)

While scientists are using the human genome to associate certain genes with disease, Dr. Hongyan Xu wants to ensure they are accounting for natural variations in those genes. ...> Full Article

Scientists sequence first female DNA (5/28/2008)

Geneticists in the Netherlands are the first to determine the DNA sequence of a woman ...> Full Article

Metagenomics of skin reveals insights into the human microbiome (5/27/2008)

The human body is home to a diverse range of microorganisms, estimated to outnumber human cells in a healthy adult by ten fold. The importance of characterizing human microbiota for understanding health and disease is highlighted by the recent launch of the Human Microbiome Project ...> Full Article

First Draft of Oil Palm Genome Completed (5/22/2008)

Knowledge of the plant and environment genomes will foster the development of improved plant feedstocks, biofertilizers, plant disease diagnostic and control solutions and renewable fuels ...> Full Article

Scientists decipher fruit tree genome for the first time (5/16/2008)

Researchers from several universities of the USA and China have sequenced for the first time papaya genome; they have also identified the DNA of a transgenic organism for the first time. ...> Full Article

Unraveling the Genomic Code for Development (5/10/2008)

Scientists have produced the first complete description of the complex network of genes that create a particular type of cell in an organism. ...> Full Article

Shaq of bacteria (5/8/2008)

The secret to an unusually large bacteria may be found in its ability to copy its genome tens of thousands of times. ...> Full Article

Superbug genome sequenced (5/8/2008)

The genome of a newly-emerging superbug, commonly known as Steno, has just been sequenced. The results reveal an organism with a remarkable capacity for drug resistance. ...> Full Article

Break it down (5/7/2008)

Genome sequence of Podospora anserina reveals unsuspected ability to use complex carbon sources ...> Full Article

Evolutionary Intricacies Of Rickettsia Pathogens Revealed (5/7/2008)

Scientists have unveiled some of the evolutionary intricacies of rickettsial pathogens by analyzing over a decade's worth of genomic data ...> Full Article

Mouse can do without man's most treasured genes (5/7/2008)

The mouse is a stalwart stand-in for humans in medical research, thanks to genomes that are 85 percent identical. But identical genes may behave differently in mouse and man ...> Full Article

Platypus genome sequence published (5/6/2008)

Platypus genetic blueprint reveals the early history of mammals ...> Full Article

New Map Reveals Dynamic Variation in Human Genome (5/4/2008)

A team of researchers has produced the first high-resolution map showing the structural variation that exists in the human genome. With the map, researchers can now begin to see how the underlying structure of one person's genome differs from that of another. ...> Full Article

Epigenetic research uncovers new targets for modification enzymes (4/28/2008)

Enzymes regulating genetic expression can be just as important as the genome itself, increasing evidence shows ...> Full Article

First draft of transgenic papaya genome yields many fruits (4/24/2008)

A broad collaboration of research institutions in the U.S. and China has produced a first draft of the papaya genome. This draft, which spells out more than 90 percent of the plant's gene coding sequence, sheds new light on the evolution of flowering plants. ...> Full Article

Scientists Show First 3-D Image of Antibody Gene (4/19/2008)

Researchers have shown for the first time how a genome is organized in three-dimensional space. ...> Full Article

Scientists develop strategy to rapidly describe outbreak strains with next-generation DNA sequencing (4/15/2008)

Rapid comparative genomic analysis for clinical microbiology ...> Full Article

Data-handling technique finds genes to be team players in curbing brain cancer cell growth (4/10/2008)

Researchers describe a new algorithm for ranking abnormal genes according to their likelihood of contributing to a cancer. And they show that a gene identified by the algorithm as a likely restrainer of tumor growth does indeed play that role in a common type of brain cancer, and is not a mere "bystander" to another restrainer gene ...> Full Article

Software developed by Boston College lab delivers speed and accuracy to genome research (3/30/2008)

Software aids researchers analyzing millions of DNA sequences ...> Full Article

Toward the ethical treatment of whole genome research participants (3/28/2008)

The ability to sequence a person's entire genome has created a whole new set of moral challenges that standard research ethics guidelines were not designed to solve ...> Full Article

First beetle genome sequenced (3/26/2008)

Sequencing the genome of the red flour beetle, also known as Tribolium castaneum, could prove of double benefit - both in understanding how organisms develop and in fighting the insect pest ...> Full Article

Plant gene clusters for natural products (3/24/2008)

scientists have found that plants may cluster the genes needed to make defence chemicals. Their findings may provide a way to discover new natural plant products of use as drugs, herbicides or crop protectants. Using a gene cluster that makes an antifungal compound in oats as a template, they uncovered a previously unknown gene cluster making a related compound in a very different species, and now want to extend the search to other plants. ...> Full Article

Bioinformatics technology provides new insight into microbial activities (3/15/2008)

Scientists may gain a new insight into the relationship between viruses and their environments thanks to a new computational technology developed by researchers at the U.S. Department of Energy's Argonne National Laboratory. This technology has already been used to identify subtle differences in the metabolic processes of microbial communities. ...> Full Article

High-School Scientists Decode DNA Sequence, Present Findings (3/14/2008)

New Jersey students publish their findings, present their work at the National Science Foundation ...> Full Article

Epigenetic changes discovered in major psychosis (3/12/2008)

New clues for uncovering the mysteries of mental illness ...> Full Article

Brown-led study rearranges some branches on animal tree of life (3/8/2008)

A study led by Brown University biologist Casey Dunn uses new genomics tools to answer old questions about animal evolution. The study is the most comprehensive animal phylogenomic research project to date, involving 40 million base pairs of new DNA data taken from 29 animal species. ...> Full Article

Giant panda genome to be sequenced (3/7/2008)

Researchers announce the launch of the International Giant Panda Genome Project ...> Full Article

Researchers Help Unlock the Genetic Secrets of Corn (3/5/2008)

Relying on a genetic "physical map" developed by University of Arizona plant scientists, researchers from Washington University, Cold Spring Harbor Laboratory, Iowa State University and the UA have completed a working draft of the corn genome. By unlocking the genetic secrets of this crop vital to U.S. agriculture, the researchers have gained information that could ultimately help society deal with drought, global warming, population pressures and increasing energy needs. ...> Full Article

All Eyes and Ears on the Corn Genome (3/3/2008)

Researchers complete draft sequence in less than three years ...> Full Article

Cancers in Dogs, Humans Share Same Genetic Basis, Say Researchers (3/2/2008)

Cancer researchers have found that humans and dogs share more than friendship and companionship - they also share the same genetic basis for certain types of cancer. Furthermore, the researchers say that because of the way the genomes have evolved, getting cancer may be inevitable for some humans and dogs. ...> Full Article

Genetic Coding Of The Pea Unraveled (3/2/2008)

The pea is one of many important crop species that is unsuited to the Agrobacterium-based genetic modification techniques that are commonly used to work with crops. Researchers have now discovered the first high-throughput forward and reverse genetics tool for the pea (Pisum sativum), could have major benefits for crop breeders around the world. ...> Full Article

Researchers help piece together the corn genome's first draft (2/28/2008)

Researchers helped write the first draft of the corn genome sequence that will be announced Thursday, Feb. 28, at the 50th Annual Maize Genetics Conference in Washington, D.C. ...> Full Article

Genome-wide profiling of epigenetic therapy in cervical cancer (2/26/2008)

In a single-arm interventional study, demethylating hydralazine and the histone deacetylase (HADC) inhibitor magnesium valproate were added to cisplatin chemoradiation in International Federation of Gynecology and Obstetrics (FIGO) stage IIIB cervical cancer treatment to assess their safety and biological effects. ...> Full Article

Structural Genomic Variation and Personalized Medicine (2/24/2008)

The ultimate goal of personalized medicine is to comprehensively identify genetic differences among persons and to correlate specific genetic features (or combinations of genetic features) with the differential risk of human diseases or the efficacy of certain therapeutic interventions. "This goal is likely to be achieved when we are able to identify all relevant forms of genetic variation in each person and are able to interpret this information in a clinically meaningful manner," said researchers from Harvard Medical School in their article recently published in The New England Journal of Medicine. ...> Full Article

Imitating monkey's 'jumping genes' could lead to new treatments for HIV (2/20/2008)

Scientists have taken a significant step in understanding how retroviruses such as HIV can move between species and the biological mechanisms behind the 'jumping genes' which make some monkeys immune. They will now use this knowledge to develop a gene therapy treatment for HIV/AIDS in humans. ...> Full Article

Identical twins not as identical as believed (2/16/2008)

Contrary to our previous beliefs, identical twins are not genetically identical. This surprising finding is presented by American, Swedish, and Dutch scientists in a study being published today in the prestigious journal American Journal of Human Genetics. The finding may be of great significance for research on hereditary diseases and for the development of new diagnostic methods. ...> Full Article

Microbial 'cheaters' help scientists ID 'social' genes (2/14/2008)

Genome-wide search for social genes turns up more than 100 cheaters ...> Full Article

Scientists find how a protein binds to genes and regulates them across the human genome (2/11/2008)

Out of chaos, control: Cornell molecular biologists have discovered how a protein called PARP-1 binds to genes and regulates their expression across the human genome. Knowing where PARP-1 is located and how it works may allow scientists to target this protein to battle common diseases, such as stroke and cancer. ...> Full Article

New DNA sequencing methods put to work (2/10/2008)

Latest efforts to boost value of high-throughput DNA sequencing detailed at genome technology conference ...> Full Article

Bacterium sequenced makes rare form of chlorophyll (2/9/2008)

Researchers have sequenced the genome of a rare bacterium that harvests light energy by making an even rarer form of chlorophyll, chlorophyll d. Chlorophyll d absorbs "red edge," near infrared, long wave length light that is invisible to the naked eye. ...> Full Article

On the front lines of the genomic revolution (2/8/2008)

Manolis Kellis, a young and fast-rising MIT researcher, uses sophisticated computational tools to investigate the genomes of a variety of organisms, including humans, mice, fruit flies and yeast, and the insights emerging from that work could lead to important findings about human development and disease. ...> Full Article

Researchers Reveal Surprises in Sea Anemone Genome (2/7/2008)

A team of international researchers, one of them a University of Maine professor, has discovered in a primitive starlet sea anemone the genes for a biochemical pathway that scientists had thought did not exist in animals. ...> Full Article

Environmental Epigenetics Has Potential for Preventing and Treating Disease (2/2/2008)

New research on environmental influences on health and disease has begun to shed light on why genetically identical individuals demonstrate different characteristics, such as susceptibility to disease. Scientists have found that environmental exposure to nutritional, chemical and physical factors can alter the epigenome. Literally meaning "above the genome," the epigenome refers to differences in gene expression that are inherited without changing the sequence of DNA. ...> Full Article

Scientists explore factors contributing to DNA mutations (1/31/2008)

A team of Penn State researchers is the first to conduct a genome-wide study to compare the relative importance of factors that contribute to DNA mutations, which are implicated in cancer and more than 40 neurological disorders. Led by assistant professor of biology Kateryna Makova, the group investigated the simultaneous effects of numerous factors that are thought to increase the susceptibility to mutations of microsatellites -- variable-length sequences of recurring DNA subunits. Microsatellites are common throughout the genomes of plants and animals. The work is described in the January issue of the journal Genome Research. ...> Full Article

A group of researchers discover a new code in the genome (1/29/2008)

The finding have been possible thanks to the calculation capacity of the MareNostrum supercomputer ...> Full Article

Genome-wide Study Shed Lights On Factors That Contribute To DNA Mutations (1/29/2008)

A team of Penn State University researchers is the first to conduct a genome-wide study to compare the relative importance of factors that contribute to DNA mutations, which are implicated in cancer and over 40 neurological disorders. Led by assistant professor of biology Kateryna Makova, the group investigated the simultaneous effects of numerous factors that are thought to increase the susceptibility to mutations of microsatellites -- variable-length sequences of recurring DNA subunits. Microsatellites are common throughout the genomes of plants and animals. ...> Full Article

Search For The 'On' Switches May Reveal Genetic Role In Development And Disease (1/26/2008)

A new resource that identifies regions of the human genome that regulate gene expression may help scientists learn about and develop treatments for a number of human diseases, according to researchers at Duke's Institute for Genome Sciences & Policy (IGSP). ...> Full Article

Knome Commences Whole-Genome Sequencing Process for First Clients (1/23/2008)

First individuals in history to have genome sequenced by a personal genomics firm ...> Full Article

International consortium announces the 1000 Genomes Project (1/23/2008)

An international research consortium today announced the 1000 Genomes Project, an ambitious effort to sequence the genomes of at least 1000 people to create the most detailed and medically useful catalogue to date of human genetic variation. ...> Full Article

'Tree Of Life' Has Lost A Branch, According To Largest Genetic Comparison Of Higher Life Forms Ever (1/22/2008)

Norwegian and Swiss biologists have made a startling discovery about the relationship between organisms that most people have never heard of. The Tree of Life must be re-drawn, textbooks need to be changed, and the discovery may also have significant impact on the development of medicines. ...> Full Article

Soybean Genome Assembly Available To Scientists (1/19/2008)

A preliminary assembly and annotation of the soybean genome, Glycine max, has been made available by the U.S. Department of Energy Joint Genome Institute (DOE JGI), to the greater scientific community to enable bioenergy research. ...> Full Article

Probing Question: What is metagenomics? (1/18/2008)

It may sound like a diet plan or a new-age religion, but to microbiologists, metagenomics is something far more important: a new way of looking at the world. ...> Full Article

A new piece in the autism puzzle (1/13/2008)

Genome scan finds missing DNA may play role in cognitive disorder ...> Full Article

Researchers report new twist in microRNA biology (1/11/2008)

Computational biology group identifies new mechanism of gene regulation ...> Full Article

Eureka Genomics Licenses Genome Analysis Tools From University of Houston (1/7/2008)

Pathogen detection, personalized medicine to benefit from new partnership ...> Full Article

Report Urges Development of Genomic Technologies for Identifying Toxic Chemicals and Understanding Individual Vulnerabilities (10/9/2007)

A new report from the National Research Council recommends that government agencies enhance their efforts to incorporate genomic data into risk assessments of chemicals and medicines, and calls for a concerted effort to fully develop these methods' potential to protect public health. Chemicals and drugs often cause health problems by altering gene expression and other cell activity, and research on these processes -- called toxicogenomic research -- could eventually lead to more-sensitive toxicity tests that can supplement current tests, the report says. Toxicogenomic tests can also pinpoint individuals with genetic vulnerabilities and help them avoid chemicals or medications that might make them ill. ...> Full Article

Hydrothermal Vents: Hot Spots Of Microbial Diversity (10/6/2007)

Thousands of new kinds of marine microbes have been discovered at two deep-sea hydrothermal vents off the Oregon coast by scientists at the MBL (Marine Biological Laboratory) and University of Washington's Joint Institute for the Study of Atmosphere and Ocean. ...> Full Article

New research funding awarded to help find cane toad Achille's heel (10/5/2007)

Researchers have hailed the Carpenter Government's decision to provide extra funding for a project that could deliver a biological answer to stopping cane toads entering the State. ...> Full Article

'Genes and Environment' grant funds close look at nature-nurture overlap in common diseases (9/25/2007)

Johns Hopkins' McKusick-Nathans Institute of Genetic Medicine is one of two gene-hunting facilities in the nation to win a new $11.7 million four-year federal grant to rigorously sort out how such environmental factors as diet, exercise, stress and addictions interact with people's individual genetic makeup to affect their risk for disorders as wide-ranging as cancer, diabetes, tooth decay and heart disease. ...> Full Article

UCI and CODA Genomics collaborate to re-engineer yeast for biofuel production (9/4/2007)

Common fungus could increase ethanol output ...> Full Article