All Articles Tagged As: rna

How short RNAs influence proteins (8/3/2008)

Protein output of genes targeted by specific microRNAs ...> Full Article

MicroRNA implicated as molecular factor in alcohol tolerance (8/1/2008)

Researchers zero in on development of alcohol tolerance ...> Full Article

Class of antibiotics can enhance gene-silencing tool (7/22/2008)

Researchers have discovered that antibiotics known as fluoroquinolones can make RNA interference more effective in the laboratory and reduce potential side effects ...> Full Article

Newly Identified Role For 'Power Plants' In Human Cells Could Lead To Targeted Therapies (7/18/2008)

Scientists have determined that human cells are able to shift important gene products into their own mitochondria, considered the power plants of cells. The finding could eventually lead to therapies for dozens of diseases. ...> Full Article

RNA emerges from DNA's shadow (7/13/2008)

EUROCORES program RNAQuality holds first conference ...> Full Article

Researchers find new mode of gene regulation in mammals (7/10/2008)

Researchers have discovered a type of gene regulation never before observed in mammals--a "ribozyme" that controls the activity of an important family of genes in several different species. ...> Full Article

Researchers identify new targets for RNAs that regulate genes (7/7/2008)

Tiny strands of genetic material called RNA â€" a chemical cousin of DNA â€" are emerging as major players in gene regulation, the process inside cells that drives all biology and that scientists seek to control in order to fight disease. ...> Full Article

Proliferating cells foil microRNA control (6/22/2008)

Biologists have discovered that proliferating cells shift the output of their genes to evade regulation by microRNAs, tiny molecules that normally suppress tumor growth. ...> Full Article

A tiny key to lock blood cells' fate (6/16/2008)

Researchers discover that microRNA directs development of certain blood cells ...> Full Article

MicroRNA controls expression of oncogenes (6/12/2008)

A new study demonstrates that microRNAs can modulate the expression of well known tumor-specific oncogenic translocation proteins and may play a significant role in some human cancers. ...> Full Article

Need microRNA processing? Get Smad (6/12/2008)

Geneticists have found that Smad proteins regulate microRNA processing. ...> Full Article

RNA induction of an epigenetic hereditary pathology (6/10/2008)

A new study shows that microinjection of RNA molecules into mouse embryos induces a hereditary form of cardiac hypertrophy that is similar to human hypertrophic cardiomyopathy ...> Full Article

Researchers observe spontaneous 'ratcheting' of single ribosome molecules (6/8/2008)

Researchers report this week that they are the first to observe the dynamic, ratchet-like movements of single ribosomal molecules in the act of building proteins from genetic blueprints. ...> Full Article

How cell's master transcribing machine achieves near perfection (6/6/2008)

Researchers describe cell's major transcriptional machinery, RNA polymerase II ...> Full Article

Possible new approach to purifying drinking water (6/4/2008)

A genetic tool used by medical researchers may also be used in a novel approach to remove harmful microbes and viruses from drinking water. ...> Full Article

Genetic pesticide developed (6/1/2008)

Researchers describe mixture that, when consumed by termites, causes them to be cripplingly deformed after molting. ...> Full Article

Whole genome activity, letter-by-letter (5/26/2008)

Global sequence and chip study examines eukaryotic transcription ...> Full Article

Scientists Visualize Gene Regulation in Living Cells (5/23/2008)

A research team has applied advanced imaging methods and computer simulations to be able to glance at the regulation of a cancer-related gene in a living cell ...> Full Article

Plant biologists discover unexpected proteins affecting small RNAs (5/18/2008)

What geneticists are learning about RNA silencing pathways in plants could be applied to cancer chemotherapy ...> Full Article

Scientists Discover New Class of Small RNAs That Regulate Gene Expression and Protect the Genome (5/17/2008)

The list of short RNAs grows longer ...> Full Article

How body size is regulated: International study discovers ten new genes related to human growth (5/15/2008)

Scientists are beginning to unravel the question why people distinctly vary in size ...> Full Article

Scientists Identify Key Roadblock to Gene Expression (5/13/2008)

A team of scientists has provided, for the first time, a detailed map of how the building blocks of chromosomes, the cellular structures that contain genes, are organized in the fruit fly Drosophila melanogaster ...> Full Article

Scientists dig deeper into the genetics of schizophrenia by evaluating microRNAs (5/12/2008)

Researchers have illuminated a window into how abnormalities in microRNAs, a family of molecules that regulate expression of numerous genes, may contribute to the behavioral and neuronal deficits associated with schizophrenia and possibly other brain disorders. ...> Full Article

MicroRNAs appear essential for retinal health (5/9/2008)

Retinas in newborn mice appear perfectly fine without any help from tiny bits of genetic material called microRNAs except for one thing - the retinas do not work. ...> Full Article

Single-celled bacterium works 24-7 (4/30/2008)

Researchers have gained the first detailed insight into the way circadian rhythms govern global gene expression in Cyanothece, a type of cyanobacterium (blue-green algae) known to cycle between photosynthesis during the day and nitrogen fixation at night. ...> Full Article

Team develops safe, effective RNA interference technique (4/29/2008)

Method holds promise for treating cancer and infection ...> Full Article

Scientists Automate Molecular Evolution (4/28/2008)

Under the control of a computer, a population of billions of genes morphed through 500 cycles of forced adaptation to emerge as molecules that could grow faster and faster on a continually dwindling source of chemical fuel ...> Full Article

Analysis Of RNA Role In Spreading Disease Advances Study Of Damaging Plant Infections (4/24/2008)

Recent research that links specific pieces of RNA to an infectious organism's duplication and spread could lead the way to the prevention of viroids, pathogens that can kill or damage food crops and other plants. ...> Full Article

Scientists Clarify a Mechanism of Epigenetic Inheritance (4/23/2008)

"Silent" DNA stays that way as a result of RNA interference during chromosome replication ...> Full Article

Fertility Expert finds Genetic Markers of an Egg's Maturity (4/21/2008)

Fertility have long been interested in understanding why so few human eggs harvested during in vitro fertilization result in pregnancies. New research narrows the list of suspects. ...> Full Article

Novel 'Gene Toggles' In Rice, World's Top Food Crop (4/15/2008)

Researchers have found a new type of molecule--a kind of "micro-switch"--that can turn off genes in rice, which is the primary source of food for more than half the world's population. ...> Full Article

Exciting new approach for identifying microRNAs (4/13/2008)

Researcher has developed a software package that can detect not only which miRNAs are active in a tissue sample, but can also discover previously unknown miRNAs. ...> Full Article

New Structure Shows Mobile RNA is Poised and Ready (4/8/2008)

Researchers have solved the structure of a group II splicing intron ...> Full Article

Physician Revolutionizes Gene Research (4/1/2008)

A dramatic new study questions some of the mechanisms underlying a new class of drugs based on Nobel Prize-winning work designed to fight diseases ranging from macular degeneration to diabetes. ...> Full Article

Less can be more, for plant breeders too (3/25/2008)

Imagine you are a rice breeder and one day within a large field you discover a plant that has just the characteristics you have been looking for. You happily take your special plant to the laboratory where you find out that the spontaneous, beneficial event was due to inactivation of a single gene. This is a great observation; however, there are many different strains grown in different parts of the world, well adapted to the particular region they grow in. How can you now transfer the inactivated gene to other strains of rice? Conventionally, you would have to go through years and years of breeding, until you have successfully transferred that single gene, without affecting all the other genes that are responsible for the target strains being so well adapted to their local environment. Would it not be great, if one could do this faster? ...> Full Article

Researchers discover the structural alphabet of RNA (3/9/2008)

A team of bioinformaticians at the Université de Montréal (UdeM) report in the March 6th edition of Nature the discovery of a structural alphabet that can be used to infer the 3D structure of ribonucleic acid (RNA) from sequence data, providing new tools to understand the role of this important class of cellular regulators. ...> Full Article

Short RNA strand helps exposed skin cells protect body from bacteria, dehydration and even cancer (3/4/2008)

Every minute, 30,000 of our outermost skin cells die so that we can live. When they do, new cells migrate from the inner layer of the skin to the surface of it, where they form a tough protective barrier. In a series of elegant experiments in mice, researchers at Rockefeller University have now discovered a tiny RNA molecule that helps create this barrier. The results not only yield new insight into how skin first evolved, but also suggest how healthy cells can turn cancerous. ...> Full Article

Researchers discover a mechanism leading to cleft palate (2/15/2008)

Work in zebrafish points to tiny gene products that regulate specific cell traffic of a key protein ...> Full Article

Australian technology licensed by billion-dollar US company (2/14/2008)

Scientists have developed a proprietary technology that will help other researchers in understanding fundamental aspects of growth, development, and disease, which has been licensed to one of the world's largest life science technology companies. ...> Full Article

Some 'Junk' DNA Is Important Guide For Nerve-cell Channel Production (2/12/2008)

Researchers at the University of Pennsylvania School of Medicine have discovered that introns, or junk DNA to some, associated with RNA are an important molecular guide to making nerve-cell electrical channels. In nerve cells, some ion channels are located in the dendrite, which branch from the cell body of the neuron. Dendrites detect the electrical and chemical signals transmitted to the neuron by the axons of other neurons. Abnormalities in the dendrite electrical channel are involved in epilepsy, neurodegenerative diseases, and cognitive disorders, among others. ...> Full Article

Scientists Discover New Gene Linked to Fragile X Syndrome (1/24/2008)

Discovery Suggests Potential Targets for Autism and Other Neurological Disorders ...> Full Article

Researcher In RNA Biology Makes Waves By Challenging Current Thinking (1/21/2008)

In the January 18th issue of Molecular Cell, Case Western Reserve University School of Medicine researcher Kristian E. Baker, Ph.D. challenges molecular biology's established body of evidence and widely-accepted model for nonsense-mediated messenger ribonucleic acid (mRNA) decay. With her collaborator, Ambro van Hoof, Ph.D. of The University of Texas Health Sciences Center, Baker directly tested the "faux 3' UTR" model and proved it could not explain how cells recognize and destroy deviant mRNA. This landmark discovery will redirect mRNA research and expand opportunities for new discoveries in understanding the cells' ability to protect itself from these potential errors. ...> Full Article

Tiny Genetic Differences Have Huge Consequences (1/20/2008)

A study led by McGill University researchers has demonstrated that small differences between individuals at the DNA level can lead to dramatic differences in the way genes produce proteins. These, in turn, are responsible for the vast array of differences in physical characteristics between individuals. ...> Full Article

Researchers report new twist in microRNA biology (1/11/2008)

Computational biology group identifies new mechanism of gene regulation ...> Full Article

Mechanics of gene transcription (1/9/2008)

The molecular machinery behind gene transcription -- the intricate transfer of information from a segment of DNA to a corresponding strand of messenger RNA -- isn't stationed in special "transcription factories" within a cell nucleus, according to Cornell researchers. Instead, the enzyme RNA polymerase II (Pol II) and other key molecules can assemble at the site of an activated gene, regardless of the gene's position. ...> Full Article